Patients and Families

Pretzel aims to bring forward new treatments that address the underlying drivers for a range of mitochondrial diseases, to better the lives of patients and their families

While our programs are still in early-stage development, they are inspired by the mitochondrial disease community and informed by engagement with key opinion leaders and patient advocacy organizations.

We aim to treat what is causing mitochondrial disease

This input has driven us to think differently about how best to treat mitochondrial disease. While the field has long focused on addressing singular symptoms, we aim to treat what is causing mitochondrial disease.

As we move our programs forward, we will continue to do so in partnership with the community.


If you are interested in learning more about Pretzel and our approach, please reach out to