A New Paradigm In Cellular Energetics
Pretzel Therapeutics is advancing a new class of medicines that target cellular energetics at its source. By focusing on the mitochondria — the engine of cellular energy—we are unlocking novel pathways to treat disease and redefining what’s possible across areas of high unmet need.
A Broad Opportunity For Therapeutic Impact
Our deep, first-in-class pipeline is designed to restore mitochondrial function, improve cellular energetics and stop or even reverse disease progression across a wide range of neurological and rare diseases driven by low mitochondrial DNA (mtDNA). By addressing a fundamental driver of disease biology, we aim to deliver meaningful impact across multiple indications.