Welcome To A New Era In Mitochondrial Therapeutics
We are leading the way for a new era of life-changing medicines for patients and families affected by mitochondrial disease. By understanding and targeting the underlying causes, we are ushering in a new treatment paradigm that addresses the drivers of mitochondrial disease, and not just singular symptoms.
A Vast Opportunity For Therapeutic Innovation
Mitochondrial disease results from cells not being able to make the energy required for organs to function properly and leads to a variety of life-altering, and often life-threatening, syndromes. Deficiency in mitochondrial DNA (mtDNA) is a common cause of mitochondrial disease, and Pretzel is designing a portfolio of programs to upregulate mtDNA to improve survival, function and quality of life.